From Novus Redux
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Poisoning is a combat skill that lets you apply poison to a bladed weapon, food, or water. The target object must be in your bag. There are 4 levels of poison. A higher poisoning skill allows the use of stronger poisons and provides a passive resistance against poison. Several instances of lesser poisons can be stacked to achieve the maximum level. Removing a strong poison may take several actions to fully cure depending on your magic, healing skills, or cure potion.